Leo has talent. Leo has instinct. Leo has a knack for knowing which toys will be hits with children. But Leo is a cockroach. And unfortunately, Ms. Mildred Splatt, the president and CEO of Waddatoy Toys, despises cockroaches. Unaware that Leo is her company's secret weapon, she is constantly trying to debug her office. Leo loves his work, but a close encounter with Mildred's shoe convinces him to seek employment elsewhere, After flying across the street to work for the competition, Leo is quickly caged and made to work as a slave for Notsogouda Toys, a maker of dangerous and poorly made toys. Unwilling to bend his toy standards to better his position, Leo plots to find a way to escape the slavish factory.